Generic Vancomycin Enriches Resistant Subpopulations of Staphylococcus aureus after Exposure in a Neutropenic Mouse Thigh Infection Model

ABSTRACT: Previous studies have shown that “bioequivalent” generic products of vancomycin are less effective in vivo against Staphylococcus aureus than the innovator compound. Considering that suboptimal bactericidal effect has been associated withemergence of resistance, we aimed to assess in vivo...

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Autores:
Rodríguez Jaramillo, Carlos Andrés
Agudelo Pérez, María
Zuluaga Salazar, Andres Felipe
Vesga Meneses, Omar
Tipo de recurso:
Article of investigation
Fecha de publicación:
2011
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/26354
Acceso en línea:
http://hdl.handle.net/10495/26354
Palabra clave:
Vancomicina
Vancomycin
Medicamentos Genéricos
Drugs, Generic
Esquema de Medicación
Drug Administration Schedule
Modelos Animales de Enfermedad
Disease Models, Animal
Staphylococcus aureus Resistente a Meticilina
Methicillin-Resistant Staphylococcus aureus
Rights
openAccess
License
http://purl.org/coar/access_right/c_abf2