Extracellular vesicles released upon stimulation with antiphospholipid antibodies : An actual direct procoagulant mechanism or a new factor in the lupus anticoagulant paradox?

ABSTRACT: Antiphospholipid antibodies (aPL) lead to a hypercoagulable state in vivo. Paradoxically, some of these autoantibodies perform as inhibitors of the coagulation cascade in vitro (a phenomenon referred to as “lupus anticoagulant”). The presence of lupus anticoagulant has been related to an i...

Full description

Autores:

Álvarez Jaramillo, Daniel
Rúa Molina, Diana Carolina
Velásquez Berrío, Manuela
Cataño Bedoya, John Ubeimar
Escudero, Carlos Alonso
Cadavid Jaramillo, Ángela Patricia

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/31499

Acceso en línea:

https://hdl.handle.net/10495/31499

Palabra clave:

Anticuerpos Antifosfolípidos
Antibodies, Antiphospholipid
Inhibidor de Coagulación del Lupus
Lupus Coagulation Inhibitor
Quinasas de Proteína Quinasa Activadas por Mitógenos
Mitogen-Activated Protein Kinase Kinases
Síndrome Antifosfolípido
Antiphospholipid Syndrome
Trombosis
Thrombosis
Vesículas Extracelulares
Extracellular Vesicles

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/