Neuroprotection and improvement of the histopathological and behavioral impairments in a murine Alzheimer's model treated with Zephyranthes carinata alkaloids
ABSTRACT: In Alzheimer’s disease (AD), amyloid beta (Aβ) plaques initiates a cascade of pathological events where the overactivation of N-methyl-D-aspartate receptors (NMDA) by excess glutamate (Glu) triggers oxidative processes that lead to the activation of microglial cells, inflammation, and fina...
- Autores:
-
Cortés Rendón, Natalie Charlotte
Sabogal Guaqueta, Angélica María
Cardona Gómez, Gloria Patricia
Osorio Durango, Edison
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2019
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/32136
- Acceso en línea:
- https://hdl.handle.net/10495/32136
- Palabra clave:
- Enfermedad de Alzheimer
Alzheimer Disease
Alcaloides de Amaryllidaceae
Amaryllidaceae Alkaloids
Relación Dosis-Respuesta a Droga
Dose-Response Relationship, Drug
Amaryllidaceae
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-nd/2.5/co/