High concentrations of atorvastatin reduce in-vitro function of conventional T and regulatory T cells

ABSTRACT: Regulatory T cells (Tregs ) modulate the magnitude of immune responses and possess therapeutic potential in an array of immune diseases. Statins reduce the activation and proliferation of conventional T cells (Tcons ), and they seem to up-regulate the frequency and function of Tregs . Howe...

Full description

Autores:

Rodríguez Perea, Ana Lucía
Rojas López, Mauricio
Velilla Hernández, Paula Andrea

Tipo de recurso:

Article of investigation

Fecha de publicación:

2019

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/32160

Acceso en línea:

https://hdl.handle.net/10495/32160

Palabra clave:

Antígenos CD
Antigens, CD
Atorvastatina
Atorvastatin
Antígeno CTLA-4
CTLA-4 Antigen
Células Cultivadas
Cells, Cultured
Citocinas
Cytokines
Citometría de Flujo
Flow Cytometry
Factores de Transcripción Forkhead
Forkhead Transcription Factors
Interleucina-2
Interleukin-2
Linfocitos T Reguladores
T-Lymphocytes, Regulatory
Factor de Necrosis Tumoral alfa
Tumor Necrosis Factor-alpha

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/