Synthesis and cytotoxic activity of per-acetylated and halogenated derivatives of nucleosides in breast cancer cells

ABSTRACT: Objectives. To make the synthesis of halogenated derivatives on the nitrogenous base and their respective acyl ester and amide type derivatives for all hydroxyl and amine groups of the uridine and cytarabine nucleosides, and evaluate cytotoxicity against breast cancer cell line. Methods. F...

Full description

Autores:
Berrío Escobar, Jhon Fernando
Pastrana Restrepo, Manuel Humberto
Galeano Jaramillo, Elkin de Jesús
Márquez Fernández, Diana Margarita
Márquez Fernández, María Elena
Martínez Martínez, Alejandro
Tipo de recurso:
Article of investigation
Fecha de publicación:
2017
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/24051
Acceso en línea:
http://hdl.handle.net/10495/24051
http://revistaseug.ugr.es/index.php/ars/article/view/6441
Palabra clave:
Neoplasias de la Mama
Breast Neoplasms
Nucleósidos
Nucleosides
Uridina
Uridine
Citarabina
Cytarabine
Citotoxicidad
Cytotoxicity
http://aims.fao.org/aos/agrovoc/c_34251
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-sa/2.5/co/