17β-Estradiol Protects Lymphocytes against Dopamine and Iron-induced Apoptosis by a Genomic-independent Mechanism : Implication in Parkinson's Disease

ABSTRACT: Dopamine (DA) in combination with iron (Fe2+) has been demonstrated to induce apoptosis in neuronal-like PC12 cells by an oxidative stress mechanism. To get a better insight of cell death and protective mechanisms in DA/Fe2+-induced toxicity, we investigated the effects of DA/Fe2+ and the...

Full description

Autores:

Jiménez Del Rio, Marlene
Vélez Pardo, Carlos Alberto

Tipo de recurso:

Article of investigation

Fecha de publicación:

2001

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/34002

Acceso en línea:

https://hdl.handle.net/10495/34002
https://www.sciencedirect.com/science/article/pii/S0306362301000829?via%3Dihub

Palabra clave:

Estradiol
Lymphocytes
Linfocitos
Dopamine
Dopamina
Apoptosis
Iron
Hierro
Parkinson Disease
Enfermedad de Parkinson

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/