Therapeutic Equivalence (TE) of 5 Generic Products (GP) of Cefotaxime (TAX) Compared with the Original Compound (OC) in the Neutropenic Mouse Thigh Infection Model (NMTIM)

ABSTRACT: Background: Contrary to accepted dogma, recent animal model data with GP demonstrated that pharmaceutical equivalence (PE) does not predi ct TE for penicillin G, ampicillin, oxacillin, amikacin, and lincomycin. Here, we report PE and TE of 5 GP of TAX legally marketed in Colombia.Methods:...