Inhibition of PbGP43 Expression May Suggest that gp43 is a Virulence Factor in Paracoccidioides brasiliensis

ABSTARCT: Glycoprotein gp43 is an immunodominant diagnostic antigen for paracoccidioidomycosis caused by Paracoccidioides brasiliensis. It is abundantly secreted in isolates such as Pb339. It is structurally related to beta-1,3-exoglucanases, however inactive. Its function in fungal biology is unkno...

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Autores:

Torres Gómez, Isaura Patricia
Hernández Ruiz, Orville
Tamayo Ossa, Diana Patricia
Muñoz Ospina, José Fernando
Pinheiro Leitao, Natanael
García Cepero, Ana María
Restrepo Moreno, Ángela
Puccia, Rosana
McEwen Ochoa, Juan Guillermo

Tipo de recurso:

Article of investigation

Fecha de publicación:

2013

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/7892

Acceso en línea:

http://hdl.handle.net/10495/7892

Palabra clave:

Fungal Proteins
Genetics Gene Expression
Immunology Genetic Vectors
Genetics Paracoccidioidomycosis
Immunology Tumor Necrosis Factor-alpha
Immunology

Rights

openAccess

License

Atribución 2.5