Meta-Analysis of 13 Genome Scans Reveals Multiple Cleft Lip/Palate Genes with Novel Loci on 9q21 and 2q32-35

ABSTRACT: Isolated or non syndromic cleft lip with or without cleft palate (CL/P) is a common birth defect with a complex etiology. A 10-cM genome scan of 388 extended multiplex families with CL/P from seven diverse populations (2,551 genotyped individuals) revealed CL/P genes in six chromosomal reg...

Full description

Autores:

Marazita, Mary
Murray, Jeffrey
Lidral, Andrew
Arcos Burgos, Oscar Mauricio
Cooper, Margaret
Goldstein, Toby
Maher, Brion
Daack Hirsch, Sandra
Schultz, Rebecca
Mansilla, Maria Adela
Field, Leigh
Liu, You-e
Prescott, Natalie
Malcolm, Sue
Winter, Robin
Ray, Ajit
Moreno Uribe, Lina Moreno
Valencia Ramírez, Luz Consuelo
Neiswanger, Katherine
Wyszynski, Diego
Bailey Wilson, Joan
Albacha-Hejazi, Hasan
Beaty, Terri
McIntosh, Iain
Hetmanski, Jacqueline
Tunçbilek, Gökhan
Edwards, Matthew
Harkin, Louise
Scott, Rodney
Roddick, Laurence

Tipo de recurso:

Review article

Fecha de publicación:

2004

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/26748

Acceso en línea:

http://hdl.handle.net/10495/26748

Palabra clave:

Cromosomas Humanos Par 2
Chromosomes, Human, Pair 2
Cromosomas Humanos Par 9
Chromosomes, Human, Pair 9
Labio Leporino - genética
Cleft Lip - genetics
Fisura del Paladar - genética
Cleft Palate - genetics
Ligamiento Genético
Genetic Linkage
Marcadores Genéticos
Genetic Markers
Predisposición Genética a la Enfermedad
Genetic Predisposition to Disease

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/