Gene expression study using real-time PCR identifies an NTR gene as a major marker of resistance to benznidazole in Trypanosoma cruzi

ABSTRACT: Background: Chagas disease is a neglected illness, with limited treatments, caused by the parasite Trypanosoma cruzi. Two drugs are prescribed to treat the disease, nifurtimox and benznidazole, which have been previously reported to have limited efficacy and the appearance of resistance by...

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Autores:
Mejía Jaramillo, Ana María
Fernández García, Geysson Javier
Palacio Muñoz, Lina Marcela
Triana Chávez, Omar
Tipo de recurso:
Article of investigation
Fecha de publicación:
2011
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/23695
Acceso en línea:
http://hdl.handle.net/10495/23695
Palabra clave:
Enfermedad de chagas
Chagas Disease
Trypanosoma cruzi
Resistencia a Medicamentos
Drug Resistance
Nifurtimox
Benznidazol
Rights
openAccess
License
http://creativecommons.org/licenses/by/2.5/co/