Gene expression study using real-time PCR identifies an NTR gene as a major marker of resistance to benznidazole in Trypanosoma cruzi
ABSTRACT: Background: Chagas disease is a neglected illness, with limited treatments, caused by the parasite Trypanosoma cruzi. Two drugs are prescribed to treat the disease, nifurtimox and benznidazole, which have been previously reported to have limited efficacy and the appearance of resistance by...
- Autores:
-
Mejía Jaramillo, Ana María
Fernández García, Geysson Javier
Palacio Muñoz, Lina Marcela
Triana Chávez, Omar
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2011
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/23695
- Acceso en línea:
- http://hdl.handle.net/10495/23695
- Palabra clave:
- Enfermedad de chagas
Chagas Disease
Trypanosoma cruzi
Resistencia a Medicamentos
Drug Resistance
Nifurtimox
Benznidazol
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/