Lovastatin delays infection and increases survival rates in AG129 mice infected with dengue virus serotype 2

ABSTARCT: It has been reported that treatment of DENV-infected cultures with Lovastatin (LOV), can affect viral assembly. The objective of this study was to evaluate the effect of LOV on the survival rate and viremia levels of DENV-2-infected AG129 mice. Methodology/Principal Findings: Mice were ino...

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Autores:
Martínez Gutiérrez, Marlén
Castellanos Parra, Jaime Eduardo
Gallego Gomez, Juan Carlos
Osorio Benitez, Jorge Emilio
Correa Londoño, Luis Alfonso
Tipo de recurso:
Article of investigation
Fecha de publicación:
2014
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/11578
Acceso en línea:
http://hdl.handle.net/10495/11578
Palabra clave:
Virus del dengue
Dengue
Treatment outcome
Lovastatina
Agente antiviral
Viremia
Virus assembly
Rights
openAccess
License
Atribución 2.5