Effect of partial depletion of CD25+ T cells on neurological deficit and tissue damage in acute cerebral ischemia rat models

ABSTRACT: Objective: To evaluate the role of regulatory T cells (Tregs) at late stages of stroke. Methods: Anti-CD25 antibody (or PBS as a control) was injected to reduce the pool of Tregs in Wistar rats; then, ischemia was induced transiently by middle cerebral artery occlusion during 60 min and re...

Full description

Autores:

Rodríguez Perea, Ana Lucía
Gutiérrez Vargas, Johanna
Rojas López, Mauricio
Cardona Gómez, Gloria Patricia
Velilla Hernandez, Paula Andrea

Tipo de recurso:

Article of investigation

Fecha de publicación:

2018

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/23062

Acceso en línea:

http://hdl.handle.net/10495/23062

Palabra clave:

Isquemia Encefálica
Brain Ischemia
Linfocitos T Reguladores
T-Lymphocytes, Regulatory
Linfocitos T
T-Lymphocytes
Transitory middle cerebral artery occlusion
Rat
Anti-CD25

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-sa/2.5/co/