Calcitriol decreases HIV-1 transfer in vitro from monocyte-derived dendritic cells to CD4 + T cells, and downregulates the expression of DC-SIGN and SIGLEC-1

ABSTRACT: Dendritic cells (DCs) promote HIV-1 transmission by acting as Trojan horses, capturing viral particles, facilitating the infection of CD4+ T-cells. Vitamin D (VitD) has shown to decrease T cell activation, reducing susceptibility to HIV-1 infection of CD4+ T-cells in vitro; however, if Vit...

Full description

Autores:

Álvarez Mesa, Natalia
González Díaz, Sandra Milena
Hernández López, Juan Carlos
Rugeles López, María Teresa
Aguilar Jiménez, Wbeimar

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/29865

Acceso en línea:

https://hdl.handle.net/10495/29865

Palabra clave:

Linfocitos T CD4-Positivos
CD4-Positive T-Lymphocytes
Calcitriol - farmacología
Calcitriol - pharmacology
Moléculas de Adhesión Celular
Cell Adhesion Molecules
Infecciones por VIH
HIV Infections
Células Dendríticas
Dendritic Cells
Lectina 1 Similar a Ig de Unión al Ácido Siálico
Sialic Acid Binding Ig-like Lectin 1

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/