In vivo effect of statins on the expression of the HIV co-receptors CCR5 and CXCR4

ABSTARCT: During the HIV-1 replication cycle, several molecules including chemokine receptors and cholesterol are crucial, and are therefore potential targets for therapeutic intervention. Indeed statins, compounds that inhibit cellular synthesis of cholesterol and have anti-inflammatory and immunom...

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Autores:
Higuita David, Edwin Andrés
Jaimes Barragán, Fabián Alberto
Rugeles López, María Teresa
Montoya Guarín, Carlos Julio
Tipo de recurso:
Article of investigation
Fecha de publicación:
2013
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/8361
Acceso en línea:
http://hdl.handle.net/10495/8361
Palabra clave:
HIV infection
Statins
CCR5
CXCR4
Viral tropism
Chemokines
Estatinas
Rights
openAccess
License
Atribución 2.5