In vivo effect of statins on the expression of the HIV co-receptors CCR5 and CXCR4

ABSTARCT: During the HIV-1 replication cycle, several molecules including chemokine receptors and cholesterol are crucial, and are therefore potential targets for therapeutic intervention. Indeed statins, compounds that inhibit cellular synthesis of cholesterol and have anti-inflammatory and immunom...

Full description

Autores:

Higuita David, Edwin Andrés
Jaimes Barragán, Fabián Alberto
Rugeles López, María Teresa
Montoya Guarín, Carlos Julio

Tipo de recurso:

Article of investigation

Fecha de publicación:

2013

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/8361

Acceso en línea:

http://hdl.handle.net/10495/8361

Palabra clave:

HIV infection
Statins
CCR5
CXCR4
Viral tropism
Chemokines
Estatinas

Rights

openAccess

License

Atribución 2.5