Role of AKT/mTORC1 pathway in pancreatic β-cell proliferation

ABSTRACT: Growth factors, insulin signaling and nutrients are important regulators of β-cell mass and function. The events linking these signals to regulation of β-cell mass are not completely understood. Recent findings indicate that mTOR pathway integrates signals from growth factors and nutrients...

Full description

Autores:
Balcázar Morales, Norman
Cecilia, Aguilar de Plata
Tipo de recurso:
Review article
Fecha de publicación:
2012
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/22206
Acceso en línea:
http://hdl.handle.net/10495/22206
Palabra clave:
Islets of Langerhans
Islotes Pancreáticos
Signal Transduction
Transducción de Señal
Cell Proliferation
Proliferación Celular
Cell cycle
Ciclo Celular
Diabetes
Type 2
AKT/PKB/mTORC1
http://aims.fao.org/aos/agrovoc/c_10361
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-nd/2.5/co/