Dendritic Cells from HIV-1 Infected Individuals are Less Responsive to Toll-like Receptor (TLR) Ligands

ABSTRACT: We compared TLR responsiveness in PBMC from HIV-1-infected and uninfected individuals using the TLR agonists: TLR7 (3M-001), TLR8 (3M-002), and TLR7/8 (3M-011). Activation and maturation of plasmacytoid dendritic cells (pDC) were measured by evaluating CD86, CD40, and CD83 expression and m...

Full description

Autores:

Martinson, Jeffrey A.
Román González, Alejandro
Tenorio, Allan R.
Montoya Guarín, Carlos Julio
Gichinga, Carolyne N.
Rugeles López, María Teresa
Tomai, Mark
Krieg, Arthur M.
Ghanekar, Smita
Baum, Linda L.
Landay, Alan L.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2007

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/26421

Acceso en línea:

http://hdl.handle.net/10495/26421

Palabra clave:

VIH
HIV
Receptor Toll-Like 8
Toll-Like Receptor 8
Receptor Toll-Like 7
Toll-like receptor 7
Infecciones por VIH
HIV Infections
Interferón-alfa
Interferon-alpha
Células Dendríticas
Dendritic Cells

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/