Increase of Frequency and Modulation of Phenotype of Regulatory T Cells By Atorvastatin Is Associatted with Decreased Lung Inflammatory Cell Infiltration in a Murine Model of Acute Allergic Asthma

ABSTRACT: Regulatory T cells (Tregs) play an important role by controlling allergic inflammation of airways. Recently, it has been shown that statins have immunomodulatory properties, probably mediated by their effects on Tregs. Therefore, we evaluated the in vivo effect of atorvastatin (ATV) on Tre...

Full description

Autores:

Blanquiceth Melendez, Yurany Patricia
Rodríguez Perea, Ana Lucía
Tabares Guevara, Jorge Humberto
Correa Londoño, Luis Alfonso
Sánchez Pino, María Dulfary
Ramírez Pineda, José Robinson
Velilla Hernández, Paula Andrea

Tipo de recurso:

Article of investigation

Fecha de publicación:

2016

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/25864

Acceso en línea:

http://hdl.handle.net/10495/25864

Palabra clave:

Linfocitos T Reguladores
T-Lymphocytes, Regulatory
Asma
Asthma
Atorvastatina
Atorvastatin
Ovalbúmina
Ovalbumin
Interleucina-10
Interleukin-10

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/