Bioavalaibility and pharmacokinetic comparison of two formulations of metformin 850 mg tablets in healthy Colombian volunteers

ABSTRACT: Purpose: The aim of this study was to compare the bioavailability of two formulations of metformin 850 mg tablets: Glucophage® from Merck Santè laboratories (reference product) and Metformin from Winthrop Pharmaceuticals de Colombia SA (test product) in healthy Colombian volunteers. Method...

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Autores:
Holguín Martínez, Gloria
Cuesta González, Fanny
Archbold Joseph, Rosendo
Restrepo Garay, Margarita María
Parra, Sergio
Peña Acevedo, Lina
Montoya Beltrán, Blanca Cecilia
Ríos Toro, Juan Carlos
Toro Pareja, Victoria Eugenia
Ruiz Corra, Adriana María
Tipo de recurso:
Article of investigation
Fecha de publicación:
2011
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/35384
Acceso en línea:
https://hdl.handle.net/10495/35384
Palabra clave:
Metformina
Metformin
Equivalencia Terapéutica
Therapeutic Equivalency
Disponibilidad Biológica
Biological Availability
Farmacocinética
Pharmacokinetics
Intercambiabilidad de Medicamentos
Interchange of Drugs
Área Bajo la Curva
Area Under Curve
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-nd/2.5/co/