Genome-wide association studies and CRISPR/Cas9-mediated gene editing identify regulatory variants influencing eyebrow thickness in humans

ABSTRACT: Hair plays an important role in primates and is clearly subject to adaptive selection. While humans have lost most facial hair, eyebrows are a notable exception. Eyebrow thickness is heritable and widely believed to be subject to sexual selection. Nevertheless, few genomic studies have exp...

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Autores:

Wu, Sijie
Zhang, Manfei
Yang, Xinzhou
Peng, Fuduan
Zhang, Juan
Tan, Jingze
Yang, Yajun
Wang, Lina
Hu, Yanan
Peng, Qianqian
Li, Jinxi
Liu, Yu
Guan, Yaqun
Chen, Chen
Hamer, Merel
Nijsten, Tamar
Zeng, Changqing
Adhikari, Kaustubh
Gallo, Carla
Poletti, Giovanni
Schuler Faccini, Lavinia
Bortolini, Maria Cátira
Canizales Quinteros, Samuel
Rothhammer, Francisco
Bedoya Berrío, Gabriel de Jesús
González José, Rolando
Li, Hui
Krutmann, Jean
Liu, Fan
Kayser, Manfred
Ruíz Linares, Andrés
Tang, Kun
XuI, Shuhua
Zhang, Liang
Jin, Li
Wang, Sijia

Tipo de recurso:

Article of investigation

Fecha de publicación:

2018

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/23704

Acceso en línea:

http://hdl.handle.net/10495/23704

Palabra clave:

Herencia
Heredity
Cejas
Eyebrows
Genética Humana
Human Genetics

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/