Diosgenone Synthesis, Anti-Malarial Activity and QSAR of Analogues of This Natural Product
ABSTRACT: Solanum nudum Dunal steroids have been reported as being antimalarial compounds; however, their concentration in plants is low, meaning that the species could be threatened by over-harvesting for this purpose. Swern oxidation was used for hemisynthesis of diosgenone (one of the most active...
- Autores:
-
Pabón Vidal, Adriana Lucía
Escobar Peláez, Gustavo
Vargas Cano, Esteban
Cruz Cañas, Víctor
Notario Bueno, Rafael
Blair Trujillo, Silvia
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2013
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/23685
- Acceso en línea:
- http://hdl.handle.net/10495/23685
- Palabra clave:
- Productos naturales
Natural products
Malaria
Steroids
Esteroides
Animal model
Modelos animales
http://aims.fao.org/aos/agrovoc/c_34312
http://aims.fao.org/aos/agrovoc/c_7407
http://aims.fao.org/aos/agrovoc/c_34782
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/