Characterization of the most promising fraction of swietenia macrophylla active against myotoxic phospholipases A2 : Identification of catechin as one of the active compounds

ABSTRACT: Background: The pharmacological effects produced by snakebite accidents involve the actions of several enzymes, of which those of the phospholipases A2 (PLA2) exhibit a wide variety of effects such as edema and myotoxicity. Some plant extracts have been antagonists of crude snake venoms an...