Search of Allosteric Inhibitors and Associated Proteins of an AKT-like Kinase from Trypanosoma cruzi
ABSTRACT: Proteins associated to the PI3K/AKT/mTOR signaling pathway are widely used targets for cancer treatment, and in recent years they have also been evaluated as putative targets in trypanosomatids parasites, such as Trypanosoma cruzi. Here, we performed a virtual screening approach to find ca...
- Autores:
-
Ochoa de Ossa, Rodrigo Alonso
Rocha Roa, Cristian
Marín Villa, Marcel
Robledo Restrepo, Sara María
Varela Miranda, Rubén Eduardo
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2018
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/32013
- Acceso en línea:
- https://hdl.handle.net/10495/32013
- Palabra clave:
- Trypanosoma cruzi
Dominios Homólogos a Pleckstrina
Pleckstrin Homology Domains
Descubrimiento de Drogas
Drug Discovery
Proteínas Proto-Oncogénicas c-akt
Proto-Oncogene Proteins c-akt
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/