Novel human recombinant N-acetylgalactosamine-6-sulfate sulfatase produced in a glyco-engineered Escherichia coli strain

Mucopolysaccharidosis IVA (MPS IVA) is a lysosomal storage disease caused by mutations in the gene encoding the lysosomal enzyme N-acetylgalactosamine-6-sulfate sulfatase (GALNS), resulting in the accumulation of keratan sulfate (KS) and chondroitin-6-sulfate (C6S). Previously, it was reported the p...

Full description

Autores:

Ramirez, Aura Maria
Cardona Ramírez, Carolina
Reyes, Luis
Tomatsu, Shunji
Jaroentomeechai, Thapakorn
DeLisa, Matthew
Sanchez, Oscar
Alméciga-Díaz, Carlos Javier

Tipo de recurso:

Article of investigation

Fecha de publicación:

2024

Institución:

Universidad de Ciencias Aplicadas y Ambientales U.D.C.A

Repositorio:

Repositorio Institucional UDCA

Idioma:

eng

OAI Identifier:

oai:repository.udca.edu.co:11158/5975

Acceso en línea:

https://repository.udca.edu.co/handle/11158/5975
https://doi.org/10.1016/j.heliyon.2024.e32555

Palabra clave:

610 - Medicina y salud::616 - Enfermedades
Mucopolisacaridosis
Escherichia coli
Acetilgalactosamina
N-linked glycosylation

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.es