Bioassay-guided fractionation in Anacardium excelsum (bert. & balb. ex kunth) skeels (anacardiaceae)

Anacardium excelsum is a tree between 15 and 50 meters high, with a thick trunk and is present in some departments of Colombia. Its nut-shaped fruits were used in the old Upar Valley by natives (Valledupar) to make Caracolí bread. Most research has been done at the forest level, but there are few ph...

Full description

Autores:
Sequeda-Castañeda, Luis Gonzalo
Celis-Zambrano, Crispín A.
Torrenegra G., Ruben Dario
Tipo de recurso:
Article of investigation
Fecha de publicación:
2021
Institución:
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Repositorio:
Repositorio Institucional UDCA
Idioma:
eng
OAI Identifier:
oai:repository.udca.edu.co:11158/4205
Acceso en línea:
https://repository.udca.edu.co/handle/11158/4205
Palabra clave:
Anacardium excelsum
Phenolic lipids
3-pentadecyl-phenol
Heptadecyl-phenol
Antioxidantes
Anacardium
Lípidos
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.es
Description
Summary:Anacardium excelsum is a tree between 15 and 50 meters high, with a thick trunk and is present in some departments of Colombia. Its nut-shaped fruits were used in the old Upar Valley by natives (Valledupar) to make Caracolí bread. Most research has been done at the forest level, but there are few phytochemical and biological activity studies. This bioguided work shows the application of antioxidant methods (ABTS+•, DPPH• and DMPD+•) in the search for active compounds present in the fraction and subfractions of greater activity. The antioxidant capacity was measured to the crude extract in ethanol and the antioxidant activity of the fractions in petroleum ether, dichloromethane, and ethanol-butanol of testa, tegument, flower, fruit, seed, bark, and leaf. Column Chromatography, Thin Layer Chromatography and Gas Chromatography coupled to Mass Spectrometry were performed on the petroleum ether fraction of testa with greater antioxidant capacity, finding the following compounds: 3- pentadec(en)il-phenol, 3-pentadecyl-phenol, 3-heptadeca(dien)il-phenol, 3-heptadec(en)ilphenol, 3-heptadecyl-phenol, 3-nonadec(en)il-phenol, ethyl ester of hexadecanoic acid, ethyl ester of heptadecanoic acid , ethyl ester of linolenic acid, hexadecanoic acid butyl ester, ethyl ether of octadecanoic acid, ethyl ester of (Z)-9-octadecenoic acid, ethyl ester of 9,12- octadecadienoic acid and ethyl ester of eicosanoic acid. The results indicate that Anacardium excelsum is a potential source of bioactive compounds.