Mass & secondary structure propensity of amino acids explain their mutability and evolutionary replacements

Why is an amino acid replacement in a protein accepted during evolution? The answer given by bioinformatics relies on the frequency of change of each amino acid by another one and the propensity of each to remain unchanged. We propose that these replacement rules are recoverable from the secondary s...

Full description

Autores:

Bohórquez, Hugo J.
Suárez, Carlos F.
Patarroyo, Manuel Elkin

Tipo de recurso:

Article of journal

Fecha de publicación:

2017

Institución:

Universidad de Ciencias Aplicadas y Ambientales U.D.C.A

Repositorio:

Repositorio Institucional UDCA

Idioma:

eng

OAI Identifier:

oai:repository.udca.edu.co:11158/2151

Acceso en línea:

https://www.nature.com/articles/s41598-017-08041-7

Palabra clave:

Péptidos
Proteinas
Peptides
Proteins
Conformational preferences
Aminoácidos

Rights

openAccess

License

Derechos Reservados - Universidad de Ciencias Aplicadas y Ambientales