The First Chemically-Synthesised, Highly Immunogenic Anti-SARS-CoV-2 Peptides in DNA Genotyped Aotus Monkeys for Human Use

Thirty-five peptides selected from functionally-relevant SARS-CoV-2 spike (S), membrane (M), and envelope (E) proteins were suitably modified for immunising MHC class II (MHCII) DNA-genotyped Aotus monkeys and matched with HLA-DRβ1* molecules for use in humans. This was aimed at producing the first...

Full description

Autores:

Patarroyo, Manuel-Elkin
Patarroyo, Manuel-Alfonso
Alba, Martha patricia
Pabon, Laura
Rugeles, Maria T.
Aguilar Jimenez, Wbeimar
Florez, Lizdany
Bermudez, Adriana
Rout, Ashok K
Griesinger, Christian
Suárez Martínez, Carlos Fernando
Aza-Conde, Jorge

Tipo de recurso:

Article of investigation

Fecha de publicación:

2021

Institución:

Universidad de Ciencias Aplicadas y Ambientales U.D.C.A

Repositorio:

Repositorio Institucional UDCA

Idioma:

eng

OAI Identifier:

oai:repository.udca.edu.co:11158/4272

Acceso en línea:

https://repository.udca.edu.co/handle/11158/4272
https://doi.org/10.3389/fimmu.2021.724060

Palabra clave:

Anticuerpos
Péptidos
Vírus del SARS
Antígenos HLA-DR

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.es