Rapid evolution of the Helicobacter pylori AlpA adhesin in a high gastric cancer risk region from Colombia

To be able to survive, Helicobacter pylori must adhere to the gastric epithelial cells of its human host. For this purpose, the bacterium employs an array of adhesins, for example, AlpA. The adhesin AlpA has been proposed as a major adhesin because of its critical role in human stomach colonization....

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Autores:
Gutiérrez Escobar, Andrés Julián
Méndez Callejas, Gina
Acevedo, Orlando
Bravo, Maria Mercedes
Tipo de recurso:
Article of journal
Fecha de publicación:
2018
Institución:
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Repositorio:
Repositorio Institucional UDCA
Idioma:
eng
OAI Identifier:
oai:repository.udca.edu.co:11158/2265
Acceso en línea:
https://peerj.com/articles/4846/
Palabra clave:
Helicobacter pylori
Píloro
Neoplasias gástricas
AlpA adhesin
Gene convergence
Helicobacter pylori
Purifying selection
Rapid evolution
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