p-Methoxyphenol: A potent and effective scavenger for solid-phase peptide synthesis

During the final step of t-Boc/Bzl, solid-phase peptide synthesis (SPPS)-protecting groups from amino acids (aa) side chains must be removed from the target peptides during cleavage from the solid support. These reaction steps involve hydrolysis with hydrogen fluoride (HF) in the presence of a nucle...

Full description

Autores:
Samacá, Jhoan
Velandia Bautista, Erika
Tabares, Luisa
Escamilla, Luis
Vanegas, Magnolia
Patarroyo, Manuel Elkin
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Repositorio:
Repositorio Institucional UDCA
Idioma:
eng
OAI Identifier:
oai:repository.udca.edu.co:11158/3240
Acceso en línea:
https://www.scopus.com/search/form.uri?display=basic
Palabra clave:
Péptidos
Aminoácidos
Síntesis química
Cleavage
Pcresolp
Pmethoxyphenol
Scavenger
Solid pphase peptide synthesis
TBoc/Bzl strategy
Rights
openAccess
License
Derechos Reservados - Universidad de Ciencias Aplicadas y Ambientales