Pharmacokinetic Appraisal of Carprofen Delivery from Intra-Articular Nanoparticles: A Population Modeling Approach in Rabbits

Osteoarthritis is frequently treated in veterinary settings with non-steroidal anti-inflammatory drugs (NSAID) such as carprofen (CP). Its action over the articular cartilage can be enhanced by increasing drug uptake into the cartilage, alongside its site of action, and anticipating its rapid distri...

Full description

Autores:
Parra Coca, Alexander
Boix Montañés, Antonio
Calpena, Ana C.
Colom, Helena
Tipo de recurso:
Article of investigation
Fecha de publicación:
2021
Institución:
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Repositorio:
Repositorio Institucional UDCA
Idioma:
eng
OAI Identifier:
oai:repository.udca.edu.co:11158/3846
Acceso en línea:
https://www.mdpi.com/2504-3900/78/1/11
https://doi.org/10.3390/IECP2020-08677
Palabra clave:
Osteoartritis
Nanopartículas
Farmacocinética
Carprofeno
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.es