Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status

Apoptosis can be triggered in two different ways, through the intrinsic or the extrinsic pathway. The intrinsic pathway is mediated by the mitochondria via the release of cytochrome C while the extrinsic pathway is prompted by death receptor signals and bypasses the mitochondria. These two pathways...

Full description

Autores:
LeJeume, Timothy M.
Tsui, Hei Yin
Parsons, Laura B.
Miller, Gerald E.
Whitted, Crystal
Lynch, Kayla E.
Ramsauer, Robert E.
Tipo de recurso:
Article of journal
Fecha de publicación:
2015
Institución:
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Repositorio:
Repositorio Institucional UDCA
Idioma:
eng
OAI Identifier:
oai:repository.udca.edu.co:11158/2571
Acceso en línea:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0142928
Palabra clave:
Apoptosis
Proteína Letal Asociada a bcl
Caspasa 10
Caspasa 8
Caspasa 9
Ciclo celular
Diferenciación celular
Línea Celular Tumoral
Proliferación Celular
Apoptosis
bcl-Associated Death Protein
Caspase 10
Caspase 8
Caspase 9
Cell Cycle
Cell Differentiation
Cell Line, Tumor
Cell Proliferation
Rights
openAccess
License
Derechos Reservados - Universidad de Ciencias Aplicadas y Ambientales