Machine learning models to select potential inhibitors of acetylcholinesterase activity from SistematX: a natural products database
Alzheimer's disease is the most common form of dementia, representing 60-70% of dementia cases. The enzyme acetylcholinesterase (AChE) cleaves the ester bonds in acetylcholine and plays an important role in the termination of acetylcholine activity at cholinergic synapses in various regions of...
- Autores:
-
Herrera-Acevedo, C.
Perdomo Madrigal, Camilo
Herrera-Acevedo, Kenyi
Coy-Barrera, Ericsson David
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2021
- Institución:
- Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
- Repositorio:
- Repositorio Institucional UDCA
- Idioma:
- spa
- OAI Identifier:
- oai:repository.udca.edu.co:11158/4277
- Acceso en línea:
- https://repository.udca.edu.co/handle/11158/4277
https://doi.org/10.1007/s11030-021-10245-z.
- Palabra clave:
- Productos Biológicos
Acetilcolinesterasa
Aprendizaje Automático
Cribado virtual
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.es