Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries
Digital
- Autores:
-
Dehghan, Mahshid
Mente, Andrew
Rangarajan, Sumathy
Mohan, Viswanathan
Lear, Scott
Swaminathan, Sumathi
Wielgosz, Andreas
Seron, Pamela
Avezum, Alvaro
Lopez-Jaramillo, Patricio
Turbide, Ginette
Chifamba, Jephat
AlHabib, Khalid F.
Mohammadifard, Noushin
Szuba, Andrzej
Khatib, Rasha
Altuntas, Yuksel
Liu, Xiaoyun
Iqbal, Romaina
Rosengren, Annika
Yusuf, Rita
Smuts, Marius
Yusufali, AfzalHussein
Li, Ning
Diaz, Rafael
Yusoff, Khalid
Kaur, Manmeet
Soman, Biju
Ismail, Noorhassim
Gupta, Rajeev
Dans, Antonio
Sheridan, Patrick
Teo, Koon
Anand, Sonia S
Yusuf, Salim
Behalf of the PURE investigators
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/6010
- Acceso en línea:
- https://doi.org/10.1093/ajcn/nqz348
https://repositorio.udes.edu.co/handle/001/6010
- Palabra clave:
- Egg intake
Dietary cholesterol
Blood lipids
Mortality
Cardiovascular disease
- Rights
- openAccess
- License
- Am J Clin Nutr 2020;111:795–803. Printed in USA. Copyright © The Author(s) 2020.
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Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries |
| title |
Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries |
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Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries Egg intake Dietary cholesterol Blood lipids Mortality Cardiovascular disease |
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Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries |
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Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries |
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Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries |
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Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries |
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Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries |
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Dehghan, Mahshid Mente, Andrew Rangarajan, Sumathy Mohan, Viswanathan Lear, Scott Swaminathan, Sumathi Wielgosz, Andreas Seron, Pamela Avezum, Alvaro Lopez-Jaramillo, Patricio Turbide, Ginette Chifamba, Jephat AlHabib, Khalid F. Mohammadifard, Noushin Szuba, Andrzej Khatib, Rasha Altuntas, Yuksel Liu, Xiaoyun Iqbal, Romaina Rosengren, Annika Yusuf, Rita Smuts, Marius Yusufali, AfzalHussein Li, Ning Diaz, Rafael Yusoff, Khalid Kaur, Manmeet Soman, Biju Ismail, Noorhassim Gupta, Rajeev Dans, Antonio Sheridan, Patrick Teo, Koon Anand, Sonia S Yusuf, Salim Behalf of the PURE investigators |
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Dehghan, Mahshid Mente, Andrew Rangarajan, Sumathy Mohan, Viswanathan Lear, Scott Swaminathan, Sumathi Wielgosz, Andreas Seron, Pamela Avezum, Alvaro Lopez-Jaramillo, Patricio Turbide, Ginette Chifamba, Jephat AlHabib, Khalid F. Mohammadifard, Noushin Szuba, Andrzej Khatib, Rasha Altuntas, Yuksel Liu, Xiaoyun Iqbal, Romaina Rosengren, Annika Yusuf, Rita Smuts, Marius Yusufali, AfzalHussein Li, Ning Diaz, Rafael Yusoff, Khalid Kaur, Manmeet Soman, Biju Ismail, Noorhassim Gupta, Rajeev Dans, Antonio Sheridan, Patrick Teo, Koon Anand, Sonia S Yusuf, Salim Behalf of the PURE investigators |
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Everest |
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Egg intake Dietary cholesterol Blood lipids Mortality Cardiovascular disease |
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Egg intake Dietary cholesterol Blood lipids Mortality Cardiovascular disease |
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Digital |
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2020 |
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2020-04-01 |
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2022-02-03T14:38:11Z |
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2022-02-03T14:38:11Z |
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Mahshid Dehghan, Andrew Mente, Sumathy Rangarajan, Viswanathan Mohan, Scott Lear, Sumathi Swaminathan, Andreas Wielgosz, Pamela Seron, Alvaro Avezum, Patricio Lopez-Jaramillo, Ginette Turbide, Jephat Chifamba, Khalid F AlHabib, Noushin Mohammadifard, Andrzej Szuba, Rasha Khatib, Yuksel Altuntas, Xiaoyun Liu, Romaina Iqbal, Annika Rosengren, Rita Yusuf, Marius Smuts, AfzalHussein Yusufali, Ning Li, Rafael Diaz, Khalid Yusoff, Manmeet Kaur, Biju Soman, Noorhassim Ismail, Rajeev Gupta, Antonio Dans, Patrick Sheridan, Koon Teo, Sonia S Anand, Salim Yusuf, on behalf of the PURE investigators, Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries, The American Journal of Clinical Nutrition, Volume 111, Issue 4, April 2020, Pages 795–803, https://doi.org/10.1093/ajcn/nqz348 |
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American Society for Nutrition |
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American Journal of Clinical Nutrition |
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Am J Clin Nutr 2020;111:795–803. Printed in USA. Copyright © The Author(s) 2020. |
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Am J Clin Nutr 2020;111:795–803. Printed in USA. Copyright © The Author(s) 2020. http://purl.org/coar/access_right/c_abf2 |
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American Journal of Clinical Nutrition |
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Dehghan, Mahshid24c90dd8-52a1-41e0-8c9a-52ee9ce29532-1Mente, Andrew9a80b664-b49e-4fce-961e-b7dd6e07a3ab-1Rangarajan, Sumathy5466c363-e515-4bd2-8537-eb839320f385-1Mohan, Viswanathane7246d73-7de3-4d86-9c7b-b9ca011e618b-1Lear, Scott8e0bbcca-8f82-4279-a446-02b2186ad662-1Swaminathan, Sumathi2df52946-d5e9-441c-b38e-cd33e6fc3722-1Wielgosz, Andreasd9d25746-66c4-498e-a328-286412ab8782-1Seron, Pamela95c6e76c-9891-4782-a399-b592acec2294-1Avezum, Alvaro8b920360-abb2-4ec8-b5ee-4e3f4e0b11eb-1Lopez-Jaramillo, Patricio9a71267b-dcb0-4d31-b37d-2d30be58d4d2-1Turbide, Ginettedd26e796-7899-401b-8c70-8ca2415030d5-1Chifamba, Jephatf2496279-e934-40b8-8f61-0039a09f03f8-1AlHabib, Khalid F.75e3b6dd-0c18-4b53-b86b-eb66c03b5e80-1Mohammadifard, Noushin24262688-da4b-4bdf-9ced-4eb264282354-1Szuba, Andrzej66d9d177-80f1-4191-9e5f-ef493dc7c253-1Khatib, Rasha7beae0a6-cfd5-4272-bf8c-1b5896fed8e5-1Altuntas, Yuksel2e2fd5d3-1ef1-4751-bdd6-0cf3901d75a4-1Liu, Xiaoyun89876bc4-6a5c-4eb5-8c94-4d8d75973585-1Iqbal, Romaina015cbc16-dd01-4e26-adff-257bb8827f50-1Rosengren, Annika923779f9-3a92-4086-b3d9-9d78974926d9-1Yusuf, Rita73629390-dae0-4d21-aca0-90da88bd2808-1Smuts, Marius4824fd9b-bfe1-4f2a-9dc8-c31f660f53f2-1Yusufali, AfzalHussein2cc4355e-2de9-46f3-8dc7-955978c66f37-1Li, Ningb6b6c183-be70-4be8-a4c3-0ab5331e06a1-1Diaz, Rafaelf2be4a74-501a-4e63-8bbd-965cbcf8c57b-1Yusoff, Khalid933db13d-f5bb-4ea6-91a5-68eea1ca9ffc-1Kaur, Manmeet857257e4-cebb-4bea-8d9b-e134b46dc72b-1Soman, Bijuf3321f5a-43bf-4982-9286-738b5a21f21a-1Ismail, Noorhassim1101b3a5-610e-458d-87ec-bde747adae7c-1Gupta, Rajeevde1826df-aac8-4d9f-9b84-f21ba704686c-1Dans, Antoniof365ef5a-7610-4022-8485-31d6d3879cd6-1Sheridan, Patrick5a728ed0-53f7-4ebc-82ef-6acfb22aa293-1Teo, Koon60475883-56ab-4acc-833d-b027ad828534-1Anand, Sonia S832ba227-ab2e-48f3-9da6-df49a0a0c8f2-1Yusuf, Salim06a836b5-f5e3-41d9-a516-9cc46e5d7948-1Behalf of the PURE investigatorsae76e952-97ef-4db4-bca0-838ac0d99b72-1Everest2022-02-03T14:38:11Z2022-02-03T14:38:11Z2020-04-01DigitalABSTRACT Background: Eggs are a rich source of essential nutrients, but they are also a source of dietary cholesterol. Therefore, some guidelines recommend limiting egg consumption. However, there is contradictory evidence on the impact of eggs on diseases, largely based on studies conducted in high-income countries. Objectives: Our aim was to assess the association of egg consumption with blood lipids, cardiovascular disease (CVD), and mortality in large global studies involving populations from low-, middle-, and high-income countries. Methods: We studied 146,011 individuals from 21 countries in the Prospective Urban Rural Epidemiology (PURE) study. Egg consumption was recorded using country-specific validated FFQs. We also studied 31,544 patients with vascular disease in 2 multinational prospective studies: ONTARGET (Ongoing Telmisartan Alone and in Combination with Ramipril Global End Point Trial) and TRANSCEND (Telmisartan Randomized Assessment Study in ACEI Intolerant Subjects with Cardiovascular Disease). We calculated HRs using multivariable Cox frailty models with random intercepts to account for clustering by study center separately within each study. Results: In the PURE study, we recorded 14,700 composite events (8932 deaths and 8477 CVD events). In the PURE study, after excluding those with history of CVD, higher intake of egg (≥7 egg/wk compared with <1 egg/wk intake) was not significantly associated with blood lipids, composite outcome (HR: 0.96; 95% CI: 0.89, 1.04; P-trend = 0.74), total mortality (HR: 1.04; 95% CI: 0.94, 1.15; P-trend = 0.38), or major CVD (HR: 0.92; 95% CI: 0.83, 1.01; P-trend = 0.20). Similar results were observed in ONTARGET/TRANSCEND studies for composite outcome (HR 0.97; 95% CI: 0.76, 1.25; P-trend = 0.09), total mortality (HR: 0.88; 95% CI: 0.62, 1.24; P-trend = 0.55), and major CVD (HR: 0.97; 95% CI: 0.73, 1.29; P-trend = 0.12). Conclusions: In 3 large international prospective studies including ∼177,000 individuals, 12,701 deaths, and 13,658 CVD events from 50 countries in 6 continents, we did not find significant associations between egg intake and blood lipids, mortality, or major CVD events. The ONTARGET and TRANSCEND trials were registered at clinicaltrials.gov as NCT00153101. The PURE trial was registered at clinicaltrials.gov as NCT03225586. Am J Clin Nutr 2020;111:795–803.Ciencias Médicas y de la Salud9 papplication/pdfhttps://doi.org/10.1093/ajcn/nqz348https://repositorio.udes.edu.co/handle/001/6010engAmerican Journal of Clinical NutritionUSA803795111Mahshid Dehghan, Andrew Mente, Sumathy Rangarajan, Viswanathan Mohan, Scott Lear, Sumathi Swaminathan, Andreas Wielgosz, Pamela Seron, Alvaro Avezum, Patricio Lopez-Jaramillo, Ginette Turbide, Jephat Chifamba, Khalid F AlHabib, Noushin Mohammadifard, Andrzej Szuba, Rasha Khatib, Yuksel Altuntas, Xiaoyun Liu, Romaina Iqbal, Annika Rosengren, Rita Yusuf, Marius Smuts, AfzalHussein Yusufali, Ning Li, Rafael Diaz, Khalid Yusoff, Manmeet Kaur, Biju Soman, Noorhassim Ismail, Rajeev Gupta, Antonio Dans, Patrick Sheridan, Koon Teo, Sonia S Anand, Salim Yusuf, on behalf of the PURE investigators, Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries, The American Journal of Clinical Nutrition, Volume 111, Issue 4, April 2020, Pages 795–803, https://doi.org/10.1093/ajcn/nqz348American Society for NutritionAmerican Journal of Clinical NutritionAm J Clin Nutr 2020;111:795–803. Printed in USA. Copyright © The Author(s) 2020.info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2https://academic.oup.com/ajcn/article/111/4/795/5713417Egg intakeDietary cholesterolBlood lipidsMortalityCardiovascular diseaseAssociation of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countriesArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Todas las AudienciasPublicationORIGINALAssociation of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries.pdfAssociation of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries.pdfDocumento Principalapplication/pdf296101https://repositorio.udes.edu.co/bitstreams/fd62b97e-5523-404f-8826-360776e0abe0/download1034c71951b5962333fa0cf12843f065MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/899a51ec-d999-4087-8be5-089114f937ca/download38d94cf55aa1bf2dac1a736ac45c881cMD52TEXTAssociation of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries.pdf.txtAssociation of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries.pdf.txtExtracted texttext/plain5https://repositorio.udes.edu.co/bitstreams/9fd7a311-47f9-4cb0-96bc-29cbbc0fc4b7/download5dbe86c1111d64f45ba435df98fdc825MD53THUMBNAILAssociation of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries.pdf.jpgAssociation of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries.pdf.jpgGenerated Thumbnailimage/jpeg11066https://repositorio.udes.edu.co/bitstreams/5bdcb217-1fea-45bd-be4b-c743b712a7ed/download5daf2d41e32ffd7661cdb7999b21c292MD54001/6010oai:repositorio.udes.edu.co:001/60102023-10-09 18:11:13.114https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |