In vitro digestion of o/w emulsions using a static model of the gastrointestinal tract

79 páginas

Autores:
Sandoval Cuellar, Camilo Eduardo
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad de la Sabana
Repositorio:
Repositorio Universidad de la Sabana
Idioma:
eng
OAI Identifier:
oai:intellectum.unisabana.edu.co:10818/38383
Acceso en línea:
http://hdl.handle.net/10818/38383
Palabra clave:
Alimentos funcionales
Bioquímica
Emulsiones
Sistema gastrointestinal
Rights
License
Attribution-NonCommercial-NoDerivatives 4.0 International
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spelling Quintanilla Carvajal, María XimenaSandoval Cuellar, Camilo EduardoMagíster en Diseño y Gestión de ProcesosColombia2019-11-27T13:58:38Z2019-11-27T13:58:38Z2019-10-20http://hdl.handle.net/10818/3838379 páginasDigestion is a complex biological process that involves interdependent steps by which food is reduced to simpler compounds that can be absorbed and used by the body. By understanding this process, it is possible to design foods with improved nutritional and healthy properties, which is known as functional foods. High Oleic Palm Oil (HOPO) is a vegetable oil extracted from OxG hybrid species, which presents a wide range of bioactive compounds that have shown to have a beneficial effect on health, which makes it an interesting potential functional food. Emulsionbased systems for HOPO encapsulation have been studied as a strategy for delivery; however, the behavior of these systems under gastrointestinal conditions has not been investigated. This project was aimed to study the behavior of High Oleic Palm Oil emulsions during simulated in vitro digestion. For this purpose, the harmonized INFOGEST method was implemented and all the required enzymatic assays and preliminary tests were performed. Once the model was placed in line, in vitro digestion experiments were carried out on two formulations of HOPO emulsions with different sizes and stability. Specific activity of 4090 U/mg, 49.40 U/mg and 6.456 U/mg of pepsin, pancreatic lipase, and trypsin, respectively, were obtained. Bile salts showed a molecular weight of 1.09 mmol/g. In vitro digestion of skim milk powder was performed in order to validate the model. Protein hydrolysis during digestion was in agreement with literature.application/pdfengUniversidad de La SabanaMaestría en Diseño y Gestión de ProcesosFacultad de IngenieríaAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_16ecAlimentos funcionalesBioquímicaEmulsionesSistema gastrointestinalIn vitro digestion of o/w emulsions using a static model of the gastrointestinal tractmasterThesispublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_bdccORIGINAL30000.JPG30000.JPGimage/jpeg24935https://intellectum.unisabana.edu.co/bitstream/10818/38383/1/30000.JPG3545fcdcbf32f15368b886e53aebeec2MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstream/10818/38383/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/38383/3/license.txtf52a2cfd4df262e08e9b300d62c85cabMD5310818/38383oai:intellectum.unisabana.edu.co:10818/383832019-11-27 08:58:40.133Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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
dc.title.es_CO.fl_str_mv In vitro digestion of o/w emulsions using a static model of the gastrointestinal tract
title In vitro digestion of o/w emulsions using a static model of the gastrointestinal tract
spellingShingle In vitro digestion of o/w emulsions using a static model of the gastrointestinal tract
Magíster en Diseño y Gestión de Procesos
Alimentos funcionales
Bioquímica
Emulsiones
Sistema gastrointestinal
title_short In vitro digestion of o/w emulsions using a static model of the gastrointestinal tract
title_full In vitro digestion of o/w emulsions using a static model of the gastrointestinal tract
title_fullStr In vitro digestion of o/w emulsions using a static model of the gastrointestinal tract
title_full_unstemmed In vitro digestion of o/w emulsions using a static model of the gastrointestinal tract
title_sort In vitro digestion of o/w emulsions using a static model of the gastrointestinal tract
dc.creator.fl_str_mv Sandoval Cuellar, Camilo Eduardo
author Magíster en Diseño y Gestión de Procesos
author_facet Magíster en Diseño y Gestión de Procesos
author_role author
dc.contributor.advisor.none.fl_str_mv Quintanilla Carvajal, María Ximena
dc.contributor.author.none.fl_str_mv Sandoval Cuellar, Camilo Eduardo
dc.contributor.author.fl_str_mv Magíster en Diseño y Gestión de Procesos
dc.subject.es_CO.fl_str_mv Alimentos funcionales
Bioquímica
Emulsiones
Sistema gastrointestinal
topic Alimentos funcionales
Bioquímica
Emulsiones
Sistema gastrointestinal
description 79 páginas
publishDate 2019
dc.date.accessioned.none.fl_str_mv 2019-11-27T13:58:38Z
dc.date.available.none.fl_str_mv 2019-11-27T13:58:38Z
dc.date.issued.none.fl_str_mv 2019-10-20
dc.type.es_CO.fl_str_mv masterThesis
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
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url http://hdl.handle.net/10818/38383
dc.language.iso.es_CO.fl_str_mv eng
language eng
dc.rights.*.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
http://purl.org/coar/access_right/c_16ec
dc.format.es_CO.fl_str_mv application/pdf
dc.coverage.spatial.es_CO.fl_str_mv Colombia
dc.publisher.es_CO.fl_str_mv Universidad de La Sabana
dc.publisher.program.es_CO.fl_str_mv Maestría en Diseño y Gestión de Procesos
dc.publisher.department.es_CO.fl_str_mv Facultad de Ingeniería
institution Universidad de la Sabana
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