In-silico study of the ionic current gradients determining left-to-right atrial frequencies during paroxysmal atrial fibrillation

Atrial fibrillation is the most prevalent cardiac arrhythmia. Paroxysmal atrial fibrillation (pAF) may occur in episodes lasting from minutes to days. Recent studies suggest that some pAF episodes present a left-to-right dominant frequency gradient caused by ionic current gradients. However, how eac...