Identifying molecularly defined antigens for a Histoplasma capsulatum-specific interferon gamma release assay [Identificación de antígenos definidos molecularmente para un ensayo de liberación de interferón-gamma específico para Histoplasma capsulatum]

Background: In a previous work we showed the feasibility of an interferon gamma release assay (IGRA) for detecting latent infection by Histoplasma capsulatum. While in that proof-of-concept study we used crude fungal extracts as antigens, the newest IGRAs developed for other infections are based on...

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Autores:

Tipo de recurso:

Fecha de publicación:

2019

Institución:

Universidad de Medellín

Repositorio:

Repositorio UDEM

Idioma:

eng
spa

OAI Identifier:

oai:repository.udem.edu.co:11407/5812

Acceso en línea:

http://hdl.handle.net/11407/5812

Palabra clave:

Histoplasma capsulatum
IGRA
Immunogenic proteins
Molecularly defined antigens
T-cell epitopes
alcohol dehydrogenase
ankyrin repeat protein
beta lactamase
chaperonin 60
DUF636 domain containing protein
epitope
fungus antigen
M antigen
proteoglycan
synthetic peptide
unclassified drug
allele
amino acid sequence
antigen detection
antigenic variation
Article
controlled study
Histoplasma capsulatum
human
immunogenicity
interferon gamma release assay
nonhuman
orthology
pathogenicity
protein analysis
sensitivity and specificity
volunteer

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