Lead (Pb++) effect on human atrial action potential under normal and atrial fibrillation conditions. In silico study

Lead (Pb++) is a toxic agent that can exert adverse effects on the cardiac human health. Pb++ blocks the Ltype Ca++ channels. A decrease in L-type calcium current (ICaL) is an important mechanism favoring atrial fibrillation. It is important to study the electrophysiological Pb++ effects on the atri...

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Autores:
Tipo de recurso:
Fecha de publicación:
2017
Institución:
Universidad de Medellín
Repositorio:
Repositorio UDEM
Idioma:
eng
OAI Identifier:
oai:repository.udem.edu.co:11407/4263
Acceso en línea:
http://hdl.handle.net/11407/4263
Palabra clave:
Atrial fibrillation
In silico models
L-type Ca++ current
Lead (Pb++)
Biomedical engineering
Calcium
Diseases
Electrophysiology
Action potential durations
Action potentials
Adverse effect
Atrial fibrillation
Calcium current
Healthy people
In-silico models
Toxic agents
Lead
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License
http://purl.org/coar/access_right/c_16ec