Lead and carbon monoxide effects on human atrial action potential. In silico study

Exposure to air pollutants like lead (Pb++) and carbon monoxide (CO), promotes the occurrence of cardiovascular diseases. Experimental studies have shown that Pb++ and CO block the L-type calcium channels, decreasing the calcium current (ICaL) and the action potential duration (APD), favoring the in...

Full description

Autores:

Tipo de recurso:

Fecha de publicación:

2017

Institución:

Universidad de Medellín

Repositorio:

Repositorio UDEM

Idioma:

eng

OAI Identifier:

oai:repository.udem.edu.co:11407/4914

Acceso en línea:

http://hdl.handle.net/11407/4914

Palabra clave:

Air pollution
Calcium
Calcium compounds
Carbon monoxide
Cardiology
Action potential durations
Action potentials
Atrial arrhythmia
Calcium current
Cardio-vascular disease
Combined effect
Computational simulation
L-type calcium channels
Lead compounds

Rights

License

http://purl.org/coar/access_right/c_16ec