TRF1 as a major contributor for telomeres’ shortening in the context of obesity

Obesity is a prevalent multifactorial chronic disorder characterized by metabolic dysregulation. Sustained pro-oxidative mediators trigger harmful consequences that reflect at systemic level and contribute for the establishment of a premature senescent phenotype associated with macromolecular damage...

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Autores:
Grun Kich, Lucas
Nevton Da Rosa, Teixeira
Mengden Von, Lúcia
De Bastiani, Marco Antônio
Parisi Migliorini, Mariana
Calixto Bortolin, Rafael
Lavandoski, Patrícia
Pierdona, Vinícius
Alves Biscaino, Letícia
Moreira Fonseca, José Cláudio
Mottin Corá, Cláudio
Jones, Marcus Herbert
Klamt, Fábio
Vontobel Padoin, Alexandre
Guma Costa R.Rodrigues, Fátima
Barbé Tuana, Florência María
Tipo de recurso:
Article of journal
Fecha de publicación:
2018
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/932
Acceso en línea:
http://hdl.handle.net/11323/932
https://repositorio.cuc.edu.co/
Palabra clave:
Aging
Obesity
Oxidative stress
Shelterin complex
Telomere length
TRF1
Rights
openAccess
License
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