Enzymatic Production Of Non-Natural Nucleoside-5′-Monophosphates By A Thermostable Uracil Phosphoribosyltransferase

The use of enzymes as biocatalysts applied to synthesis of modified nucleoside-5′-monophosphates (NMPs) is an interesting alternative to traditional multistep chemical methods which offers several advantages, such as stereo-, regio-, and enantioselectivity, simple downstream processing, and mild rea...