Sustainable production of nucleoside analogues by a high-efficient purine 2′- deoxyribosyltransferase immobilized onto Ni2+ chelate magnetic microparticles

The present work aims to develop a magnetic biocatalyst for customized production of nucleoside analogues using mutant His-tagged purine 2′-deoxyribosyltransferase from Trypanosoma brucei (TbPDTV11S) immobilized onto Ni2+ chelate magnetic iron oxide porous microparticles (MTbPDTV11S). Biochemical ch...

Full description

Autores:

Del Arco, Jon
Jordaan, Justin
Moral Dardé, Verónica
Fernández Lucas, Jesús

Tipo de recurso:

Article of investigation

Fecha de publicación:

2019

Institución:

Corporación Universidad de la Costa

Repositorio:

REDICUC - Repositorio CUC

Idioma:

eng

OAI Identifier:

oai:repositorio.cuc.edu.co:11323/10739

Acceso en línea:

https://hdl.handle.net/11323/10739
https://repositorio.cuc.edu.co/

Palabra clave:

Enzyme immobilization
Bioprocesses
Nucleoside analogues
2′-Deoxyribosyltransferases

Rights

openAccess

License

Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)