N-Ribosyltransferase From Archaeoglobus veneficus: A Novel Halotolerant and Thermostable Biocatalyst for the Synthesis of Purine Ribonucleoside Analogs

Nucleoside-2′-deoxyribosyl-transferases (NDTs) catalyze a transglycosylation reaction consisting of the exchange of the 2′-deoxyribose moiety between a purine and/or pyrimidine nucleoside and a purine and/or pyrimidine base. Because NDTs are highly specific for 2′-deoxyribonucleosides they generally...

Full description

Autores:

Acosta, Javier
Del Arco, Jon
Pisabarro, Victor
Gago, Federico
Fernández-Lucas, Jesús

Tipo de recurso:

Article of journal

Fecha de publicación:

2020

Institución:

Corporación Universidad de la Costa

Repositorio:

REDICUC - Repositorio CUC

Idioma:

eng

OAI Identifier:

oai:repositorio.cuc.edu.co:11323/6474

Acceso en línea:

https://hdl.handle.net/11323/6474
https://doi.org/10.3389/fbioe.2020.00593
https://repositorio.cuc.edu.co/

Palabra clave:

Nucleosides
Extremophiles
Nucleoside 2′-deoxyribosyltransferase
Transglycosylation
Homology modeling

Rights

openAccess

License

CC0 1.0 Universal