Green production of cladribine by using immobilized 2 0 -deoxyribosyltransferase from lactobacillus delbrueckii stabilized through a double covalent/entrapment technology

Nowadays, enzyme-mediated processes offer an eco-friendly and efficient alternative to the traditional multistep and environmentally harmful chemical processes. Herein we report the enzymatic synthesis of cladribine by a novel 2′-deoxyribosyltransferase (NDT)-based combined biocatalyst. To this end,...

Full description

Autores:

Wanda Rivero, Cintia
García, Natalia Soledad
Fernández-Lucas, Jesús
Betancor, Lorena
Romanelli, Gustavo
Trelles, Jorge Abel

Tipo de recurso:

Article of journal

Fecha de publicación:

2021

Institución:

Corporación Universidad de la Costa

Repositorio:

REDICUC - Repositorio CUC

Idioma:

eng

OAI Identifier:

oai:repositorio.cuc.edu.co:11323/8223

Acceso en línea:

https://hdl.handle.net/11323/8223
https://doi.org/10.3390/biom11050657
https://repositorio.cuc.edu.co/

Palabra clave:

Biomimetic silica
Enzyme immobilization
Glutaraldehyde
Entrapment
Calcium alginate
Antineoplastic drug

Rights

openAccess

License

CC0 1.0 Universal