Synthesis and in vivo proof of concept of a BODIPY-based fluorescent probe as a tracer for biodistribution studies of a new anti-Chagas agent

The potential use of amide-containing thiazoles, especially (2E,2Z)-3-allyl-4-[((E)-4-cinnamylpiperazin-1-yl)carbonyl]-2-[2-((E)-3-(furan-2-yl)propenylidene)hydrazono]-2,3-dihydrothiazole (1), as drugs for the treatment of Chagas disease has been recently described. The therapeutic application of 1...

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Autores:

Rodríguez, Gonzalo
Nargoli, Javier
López, Andrés
Moyna, Guillermo
Álvarez, Guzmán
Fernández, Marcelo
Osorio Martinez, Carlos Alberto
González, Mercedes Florencia
Cerecetto, Hugo Eduardo

Tipo de recurso:

Article of journal

Fecha de publicación:

2017

Institución:

Corporación Universidad de la Costa

Repositorio:

REDICUC - Repositorio CUC

Idioma:

eng

OAI Identifier:

oai:repositorio.cuc.edu.co:11323/1935

Acceso en línea:

http://hdl.handle.net/11323/1935
https://repositorio.cuc.edu.co/

Palabra clave:

Biodistributions
Chagas disease
Fluorescent probes
Fluorescent tracers
In-vitro
Pre-clinical
Proof of concept
Therapeutic Application

Rights

openAccess

License

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