Enzymatic Synthesis Of Therapeutic Nucleosides Using A Highly Versatile Purine Nucleoside 2’-Deoxyribosyltransferase From Trypanosoma Brucei
The use of enzymes for the synthesis of nucleoside analogues offers several advantages over multistep chemical methods, including chemo-, regio- and stereoselectivity as well as milder reaction conditions. Herein, the production, characterization and utilization of a purine nucleoside 2’-deoxyribosy...
- Autores:
-
Pérez, Elena
Sánchez Murcia, Pedro Alejandro
Jordaan, Justin
Blanco, María Dolores
Mancheño, José Miguel
Gago, Federico
Fernandez Lucas, Jesus
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2018
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/1015
- Acceso en línea:
- https://hdl.handle.net/11323/1015
https//doi.org/10.1002/cctc.201800775
https://repositorio.cuc.edu.co/
- Palabra clave:
- 2‘-Deoxy-Ribosyltransferase
Biocatalysis
Enzyme Immobilization
Molecular Dynamics
Nucleoside Analogues
- Rights
- openAccess
- License
- Atribución – No comercial – Compartir igual