Hypoxanthine-Guanine Phosphoribosyltransferase/adenylate Kinase From Zobellia galactanivorans: A Bifunctional Catalyst for the Synthesis of Nucleoside-5′-Mono-, Di- and Triphosphates

In our search for novel biocatalysts for the synthesis of nucleic acid derivatives, we found a good candidate in a putative dual-domain hypoxanthine-guanine phosphoribosyltransferase (HGPRT)/adenylate kinase (AMPK) from Zobellia galactanivorans (ZgHGPRT/AMPK). In this respect, we report for the firs...

Full description

Autores:

Acosta, Javier
Del Arco, Jon
Del Pozo, Maria Luisa
Herrera, Beliña
Clemente-Suárez, Vicente Javier
Berenguer, José
Hidalgo, Aurelio
Fernández-Lucas, Jesús

Tipo de recurso:

Article of journal

Fecha de publicación:

2020

Institución:

Corporación Universidad de la Costa

Repositorio:

REDICUC - Repositorio CUC

Idioma:

eng

OAI Identifier:

oai:repositorio.cuc.edu.co:11323/6477

Acceso en línea:

https://hdl.handle.net/11323/6477
https://doi.org/10.3389/fbioe.2020.00677
https://repositorio.cuc.edu.co/

Palabra clave:

Enzymatic synthesis
Nucleotides
Phosphoribosyltransferase
Nucleoside-5cpsdummy′-monophosphate kinase
Dual domain protein

Rights

openAccess

License

CC0 1.0 Universal