Taylor-made production of pyrimidine nucleoside-5′-monophosphate analogues by highly stabilized mutant uracil phosphoribosyltransferase from Toxoplasma gondii

Nowadays, enzymatic synthesis of nucleotides is an efficient and sustainable alternative to chemical methodologies. In this regard, after the biochemical characterization of wild-type and mutant uracil phosphoribosyltransferases from Toxoplasma gondii (TgUPRT, TgUPRT2, and TgUPRT3), TgUPRT2 was sele...

Full description

Autores:

Acosta, Javier
Nguyen, Kim
C. Spitale, Robert
Fernández-Lucas, Jesús

Tipo de recurso:

Article of journal

Fecha de publicación:

2021

Institución:

Corporación Universidad de la Costa

Repositorio:

REDICUC - Repositorio CUC

Idioma:

eng

OAI Identifier:

oai:repositorio.cuc.edu.co:11323/8625

Acceso en línea:

https://hdl.handle.net/11323/8625
https://doi.org/10.1016/j.biortech.2021.125649
https://repositorio.cuc.edu.co/

Palabra clave:

Nucleoside-5′-monophosphates
Phosphoribosyltransferases
Structure-guided immobilization

Rights

embargoedAccess

License

CC0 1.0 Universal