Characterization and modulation of microglial phenotypes in an animal model of severe sepsis

We aim to characterize the kinetics of early and late microglial phenotypes after systemic inflammation in an animal model of severe sepsis and the effects of minocycline on these phenotypes. Rats were subjected to CLP, and some animals were treated with minocycline (10 ug/kg) by i.c.v. administrati...

Full description

Autores:
Michels, Monique
Rocha Abatti, Mariane
Avila, Pricila
Vieira, Andriele
Borges, Heloisa
Carvalho Junior, Celso
Wendhausen, Diogo
Gasparotto, Juciano
Tiefensee Ribeiro, Camila
Moreira, José Cláudio Fonseca
Pens Gelain, Daniel
Dal‐Pizzol, Felipe
Tipo de recurso:
Article of journal
Fecha de publicación:
2019
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/5646
Acceso en línea:
https://hdl.handle.net/11323/5646
https://repositorio.cuc.edu.co/
Palabra clave:
M1/M2
Microglia
Inflammation
Microglial polarization
Phenotypes
Sepsis
Rights
openAccess
License
CC0 1.0 Universal