Computational fishing of new DNA methyltransferase inhibitors from natural products

DNA methyltransferase inhibitors (DNMTis) have become an alternative for cancer therapies. However, only two DNMTis have been approved as anticancer drugs, although with some restrictions. Natural products (NPs) are a promising source of drugs. In order to find NPs with novel chemotypes as DNMTis, 4...

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Autores:
Tipo de recurso:
Fecha de publicación:
2015
Institución:
Ministerio de Ciencia, Tecnología e Innovación
Repositorio:
Repositorio Minciencias
Idioma:
eng
OAI Identifier:
oai:repositorio.minciencias.gov.co:20.500.14143/34166
Acceso en línea:
http://repositorio.colciencias.gov.co/handle/11146/34166
Palabra clave:
Biología vegetal
Aceites vegetales
Productos químicos
Anticancer
Screening
QSAR
Docking
Cluster
Biotecnología
Tecnología química
Química agrícola
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License
http://purl.org/coar/access_right/c_f1cf