Selective activity of 2,4-diaryl-1,2,3,4-tetrahydroquinolines on Trypanosoma cruzi epimastigotes and amastigotes expressing β-galactosidase

The growth inhibitory effect on Trypanosoma cruzi epimastigotes and the unspecific cytotoxicity over NCTC-929 fibroblasts of two series of previously synthesized 2,4-diaryl-1,2,3,4-tetrahydroquinolines (THQ), have been studied in vitro and compared with those of benznidazole (BZ). Derivatives AR39,...

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Autores:

Tipo de recurso:

Fecha de publicación:

2013

Institución:

Ministerio de Ciencia, Tecnología e Innovación

Repositorio:

Repositorio Minciencias

Idioma:

eng

OAI Identifier:

oai:repositorio.minciencias.gov.co:20.500.14143/34187

Acceso en línea:

http://repositorio.colciencias.gov.co/handle/11146/34187

Palabra clave:

Plantas medicinales
Trypanosoma cruzi
Productos químicos
Trypanosoma cruzi
Tetrahydroquinolines
Cytotoxicity
Lipinski’s rule
OSIRIS software
Bioquímica vegetal
Aceites esenciales
Bioquímica vegetal
Tecnología química

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