Unfolding Ubiquitin by force: water mediated H-bond destabilization
Using the “pull and wait” (PNW) simulation protocol at 300 K, we studied the unfolding by force of an ubiquitin molecule. PNW was implemented in the CHARMM program using an integration time step of 1 fs and a uniform dielectric constant of 1. The ubiquitin molecule, initially solvated, was put under...
- Autores:
- Tipo de recurso:
- article
- Fecha de publicación:
- 2012
- Institución:
- Pontificia Universidad Javeriana
- Repositorio:
- Repositorio Universidad Javeriana
- Idioma:
- eng
- OAI Identifier:
- oai:repository.javeriana.edu.co:10554/31738
- Acceso en línea:
- http://revistas.javeriana.edu.co/index.php/scientarium/article/view/4024
http://hdl.handle.net/10554/31738
- Palabra clave:
- null
H-bond, molecular dynamics, PNW, mechanical unfolding
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H-bond, molecular dynamics, PNW, mechanical unfolding
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- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional